Fig. 6From: The development of a GPR44 targeting radioligand [11C]AZ12204657 for in vivo assessment of beta cell massIn vitro autoradiography total binding in pancreas by 1 nM [4-3H-methyl]-AZ12204657 incubated for 3 h from healthy human subjects (a). Non-specific binding is determined in the presence of 20 μM AZD3825 (b). The pancreatic binding of tracer is displaceable and concentrated to the islet of Langerhans (results are from two independent experiments with measurements performed in duplicates)Back to article page