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Fig. 5 | EJNMMI Research

Fig. 5

From: Optimization of a dedicated protocol using a small-voxel PSF reconstruction for head-and-neck 18FDG PET/CT imaging in differentiated thyroid cancer

Fig. 5

A 40-year-old male patient with a 20-mm papillary DTC was referred for 18FDG PET/CT in November 2015. He had previously undergone total thyroidectomy in 2001 and remission was observed during yearly follow-up until 2014. In 2015, the serum Tg was still < 0.04 ng/ml but serum TgAb appeared. Head-and-neck PET was performed. Axial PET on the same level was shown with 3D-OSEM (a) and PSFallpass (b) reconstructions. No abnormal 18FDG focus was reported on 3D-OSEM-reconstructed HN PET (at 10 min: SUVmax = 1.44, TBR = 0.99). On the PSFallpass-reconstructed HN PET data sets, a faint focal 18FDG uptake in the right-sided central compartment was scored as probably malignant (score 4) at 10 min (SUVmax = 2.26, TBR = 1.46), corresponding to a 5 × 3 mm lymph node on CT scan (red arrows). c Pathology confirmed that this abnormal focus was truly malignant. The size of the tumour deposit in the right central lymph node was 5 mm (HES staining, × 2.5; black arrows)

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