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EJNMMI Research

Table 3 Mean FP-CIT SPECT and FE-PE2I PET binding in HC and patients

From: Dopamine transporter imaging with [18F]FE-PE2I PET and [123I]FP-CIT SPECT—a clinical comparison

 

HC, n = 28

PS, n = 22

Sig.

Effect size

Mean (SD)

Mean (SD)

p

Glass’s Δ

FP-CIT, SUR

 Caudate

3.12

(0.46)

2.35

(0.79)

< 0.001

1.67

 Putamen

2.62

(0.47)

1.43

(0.68)

< 0.001

2.54

 Striatum

2.80

(0.45)

1.77

(0.69)

< 0.001

2.29

FE-PE2I, BPND

 Caudate

2.93

(0.46)

2.29

(0.80)

0.004

1.40

 Putamen

3.78

(0.46)

1.98

(1.07)

< 0.001

3.90

 Striatum

3.40

(0.43)

2.12

(0.90)

< 0.001

2.95

 SN

0.72

(0.07)

0.60

(0.10)

< 0.001

1.62

FE-PE2I, SUVR

 Caudate

5.54

(0.75)

4.61

(1.28)

0.006

1.24

 Putamen

6.75

(0.83)

3.97

(1.71)

< 0.001

3.36

 Striatum

6.21

(0.76)

4.26

(1.44)

< 0.001

2.57

 SN

2.08

(0.12)

1.88

(0.18)

< 0.001

1.67

  1. Measures of DAT availability in the caudate, putamen, striatum, and SN. Mean = averaged left and right side
  2. SUR specific uptake ratio, BPND binding potential relative to non-displaceable binding, SUVR specific uptake value ratio, HC healthy controls, PS parkinsonian syndrome, SN substantia nigra
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