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EJNMMI Research
Fig. 4 | EJNMMI Research

Fig. 4

From: Synthesis and in vitro and in vivo evaluation of urea-based PSMA inhibitors with increased lipophilicity

Fig. 4

Small-animal positron emission tomography. a PET images (MIP at 1 h p.i., 0–10% ID/g) of LNCaP tumor-bearing CD-1 nu/nu mice after injection of 68Ga-10 (0.28 nmol), 68Ga-10 co-injected with PMPA (8 mg/kg), 68Ga-11 (0.23 nmol), and 68Ga-11 co-injected with PMPA (8 mg/kg), respectively (n=1). Time-activity curves (logarithmic plot) for the blood pool (heart), muscle, kidney, and tumor as derived from OSEM 3D reconstructed dynamic PET scan for 1.5 h after injection of b 68Ga-10 and c 68Ga-11 (n = 1, respectively)

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