Table 1 Percentage of incorporation of 213BiIII by chelate ligands (pH 5.5, V = 0.1 mL, reaction time 5 min at 25 °C). Data represent mean values ± SD, n = 3
c [μM] | DOTP | DOTPH | DOTPOEt | DOTPI | CHX-A"-DTPA | DOTA |
|---|---|---|---|---|---|---|
100 | 92.9 ± 5.6 | 91.6 ± 0.4 | 79.6 ± 3.6 | 84.8 ± 4.0 | 91.4 ± 5.1 | 61.0 ± 7.3 |
30 | 88.8 ± 10.7 | 83.8 ± 11.9 | 70.8 ± 8.8 | 70.6 ± 11.9 | 78.6 ± 6.9 | 37.4 ± 6.9 |
10 | 87.2 ± 11.8 | 82.5 ± 12.4 | 70.6 ± 6.5 | 61.5 ± 5.1 | 75.7 ± 11.8 | 15.6 ± 6.7 |
3 | 86.5 ± 11.2 | 80.4 ± 9.7 | 66.0 ± 9.5 | 58.1 ± 2.4 | 75.3 ± 12.6 | 11.2 ± 0.9 |
1 | 89.3 ± 7.2 | 78.4 ± 10.6 | 63.5 ± 11.2 | 47.9 ± 2.6 | 66.6 ± 20.6 | 5.1 ± 4.6 |
0.3 | 85.4 ± 2.5 | 75.0 ± 14.8 | 56.0 ± 9.9 | 27.0 ± 2.0 | 41.5 ± 8.5 | |
0.1 | 85.0 ± 5.2 | 66.7 ± 3.1 | 42.4 ± 13.2 | 15.4 ± 9.5 | 22.1 ± 10.1 | |
0.03 | 67.6 ± 3.5 | 42.2 ± 2.8 | 27.5 ± 11.2 | 11.8 ± 3.5 | ||
0.01 | 32.4 ± 4.6 | 20.2 ± 5.7 | 16.7 ± 6.4 | |||
0.003 | 13.6 ± 4.1 | 3.8 ± 0.9 | 6.6 ± 3.5 | |||
0.001 | 4.3 ± 1.6 | 0.9 ± 1.3 |