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Table 2 Summary of runs-test results and totaled AIC, BIC, and MSEP scores for compartment model fits to all 30 whole tumor FMISO TACs. Lowest totaled AIC, BIC, and MSEP scores are underlined, indicating the best model according to those measures

From: Whole tumor kinetics analysis of 18F-fluoromisonidazole dynamic PET scans of non-small cell lung cancer patients, and correlations with perfusion CT blood flow

Model 2C3K 2C4K 3C5K 3C6K 4C7K 4C8K
Runs-test passes from fits to all 30 TACs
Runs 0 6 25 26 30 30
Information criteria and cross-validation scores summed for all TACs
AIC 13,970 8600 1544 1554 1557 1644
BIC 14,174 8836 1813 1840 1850 1945
MSEP 219 131 24.6 26.9 24.8 27.9
Numbers of TACs for which each model has the lowest scores
AIC 0 0 21 3 6 0
BIC 0 0 22 3 5 0
MSEP 0 0 24 3 3 0