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Fig. 4 | EJNMMI Research

Fig. 4

From: The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist

Fig. 4

Dissociation kinetics of the cell surface bound radioligands on HEK293-rsst2 cells. Dissociation kinetics of membrane bound 177Lu-SS-03 (circle) and 99mTc-SS-04 (square) as measured with HEK293-rsst2 cells. The profile illustrates the varying degree of dissociation kinetics exhibited by 177Lu-SS-03 (koff = 0.037 min-1 and t1/2 = 18.66 min) and 99mTc-SS-04 (koff = 0.040 min-1 and t1/2 = 17.24 min). Values and standard deviations are the result of two independent experiments with triplicates in each experiment. The rate constants were determined by fitting to a pseudofirst order reaction using GraphPad Prism

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