Fig. 2

Multi-modality imaging characteristics in the patient (case 5) with a left frontal cortical infarction on diffusion-weighted imaging (DWI) (a). Low ¹⁸F-THK-5351 uptake is noted in the ischemic core, and high uptake is noted in the peri-ischemic area over the corona radiata, the genu of the corpus callosum, and in the bilateral frontal areas (b, c). The ROI for ¹⁸F-THK-5351 retention is drawn in the peri-ischemic area, and a mirrored ROI is placed in the contralateral hemisphere as the control (d). There is a decreased fractional anisotropy (FA) on diffusion tensor imaging (e) (filled arrow) in the peri-ischemic area with increased ¹⁸F-THK-5351 retention as compared to the contralateral side (empty arrow). No corresponding white matter change is noted on the follow-up FLAIR image (f)