Table 2 Comparison of the K1 values from the optimal time sampling (12 × 5″-8 × 30″) and K1 values from the other time samplings for clinical validation

5 × 60″

0.600 ± 0.232

< 0.001

10 × 30″

0.573 ± 0.184

< 0.001

15 × 15″–1 × 75″

0.511 ± 0.167

< 0.001

6 × 10″–8 × 30″

0.480 ± 0.150

< 0.001

12 × 5″–8 × 30″

0.465 ± 0.149

N/A

10 × 5″–4 × 10–3 × 20″–5 × 30″

0.463 ± 0.145

0.644

8 × 3″–8 × 12″–6 × 30″

0.453 ± 0.139

< 0.001