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EJNMMI Research

Table 1 Demographic information

From: PET radioligand binding to translocator protein (TSPO) is increased in unmedicated depressed subjects

 

Healthy controls

MDD-unmedicated

MDD-medicated

 

(n = 20)

(n = 12)

(n = 16)

 

Mean

SD

Mean

SD

Mean

SD

F (2,45)

p

Age

31.60

10.36

33.80

8.66

44.60

9.74

8.54

.001

BMI (kg/m2)

26.01

4.06

27.50

5.29

28.10

4.99

0.93

.40

Age of onset (years)

–

–

18.42

5.6

17.81

5.59

0.08

.78

Current episode (months)

–

–

40.67

59.55

57.44

92.86

0.30

.59

Length of illness (years)a

–

–

16.21

8.75

26.98

10.42

8.19

.008

MADRS total score

0.30

0.57

31.75

3.62

31.00

4.40

573.73

< .0001

 

n

%

n

%

n

%

X 2

p

Sex (female)

10

50

5

42

6

38

0.59

.74

Race (Caucasian)

10

50

9

75

15

94

8.37

.02

Binding affinity (high)

12

60

10

83

9

56

2.51

.29

  1. MDD major depressive disorder, BMI body mass index, MADRS Montgomery-Asberg Depression Rating Scale
  2. aMissing data for n = 1 in MDD-medicated
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