Impact of time-of-flight PET on quantification accuracy and lesion detection in simultaneous 18F-choline PET/MRI for prostate cancer

Muehlematter, Urs J.; Nagel, Hannes W.; Becker, Anton; Mueller, Julian; Vokinger, Kerstin N.; de Galiza Barbosa, Felipe; ter Voert, Edwin E. G. T.; Veit-Haibach, Patrick; Burger, Irene A.

doi:10.1186/s13550-018-0390-8

EJNMMI Research

Table 6 Readout results

From: Impact of time-of-flight PET on quantification accuracy and lesion detection in simultaneous ¹⁸F-choline PET/MRI for prostate cancer

Nr.	Prostate cancer detection			Lymph node metastasis			Lymph node metastases count			Osseous metastasis			Osseous metastases count
	Ref^a	TOF (R1^b/R2^c/R3^d/R4^e)	Nn-TOF (R1^b/R2^c/R3^d/R4^e)	Ref	TOF (R1/R2/R3/R4)	Non-TOF (R1/R2/Rd./R4)	Ref	TOF (R1/R2/R3/R4)	Non-TOF (R1/R2/Rd./R4)	Ref	TOF (R1/R2/R3/R4)	Non-TOF (R1/R2/Rd./R4)	Ref	TOF (R1/R2/R3/R4)	Non-TOF (R1/R2/Rd./R4)
1	Y^f	Y/Y/Y/Y	Y/Y/Y/Y	Y	N/N/N/Y	N/N/N/Y	1	0/0/0/1	0/0/0/1	N	N/N/N/Y	N/N/N/Y	0	0/0/0/1	0/0/0/1
2	N^g	N/N/N/N	N/N/N/N	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
3	N	N/N/N/N	N/N/N/N	Y	Y/Y/Y/Y	N/Y/Y/Y	1	1/1/1/3	0/1/1/3	N	N/N/N/Y	N/N/N/N	0	0/0/0/6	0/0/0/0
4	Y	Y/Y/Y/Y	Y/Y/Y/Y	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0	Y	Y/Y/Y/Y	Y/Y/Y/Y	6^h	6/6/6/6	6/6/6/6
5	Y	Y/Y/N/Y	Y/N/N/Y	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
6	N	N/N/N/N	N/N/N/N	Y	Y/Y/Y/Y	Y/Y/N/N	2	2/3/2/2	1/2/0/0	Y	Y/Y/Y/Y	Y/Y/Y/Y	6	5/6/6/6	5/6/6/6
7	Y	Y/Y/Y/Y	Y/Y/N/Y	N	N/N/N/N	Y/N/N/N	0	0/0/0/0	1/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
8	Y	Y/Y/Y/Y	Y/Y/Y/Y	Y	Y/Y/Y/Y	Y/Y/N/Y	1	1/1/1/1	2/1/0/1	Y	Y/Y/N/Y	Y/N/N/Y	1	1/1/0/1	1/0/0/1
9	Y	Y/Y/Y/Y	Y/Y/Y/Y	N	N/Y/N/N	N/N/N/N	0	0/2/0/0	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
10	Y	Y/Y/Y/Y	Y/Y/Y/Y	Y	Y/N/N/N	Y/N/N/N	1	1/0/0/0	1/0/0/0	Y	Y/Y/Y/Y	Y/Y/Y/Y	6	6/6/6/6	6/0/6/6
11	Y	Y/Y/N/Y	Y/Y/Y/Y	N	Y/N/N/N	N/N/N/N	0	1/0/0/0	0/0/0/0	N	N/N/Y/N	N/N/Y/N	0	0/0/1/0	0/0/1/0
12	Y	Y/Y/Y/Y	Y/Y/N/Y	Y	Y/Y/Y/Y	Y/Y/Y/Y	6	6/6/6/6	5/6/6/6	Y	Y/Y/Y/Y	Y//Y/Y	5	4/3/1/3	4/6/1/3
13	Y	Y/Y/Y/Y	Y/Y/Y/Y	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
14	N	N/N/N/Y	N/N/N/Y	N	N/Y/N/Y	N/N/N/Y	0	0/2/0/2	0/0/0/2	Y	Y/N/N/N	N/N/Y/N	2	2/0/0/0	0/0/1/0
15	N	N/N/N/N	N/N/N/N	N	N/Y/N/N	N/N/N/N	0	0/1/0/0	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
16	N	N/Y/N/N	N/Y/N/N	Y	Y/Y/Y/Y	Y/Y/Y/Y	4	3/4/1/5	2/3/2/2	Y	Y/Y/N/N	Y/N/N/N	2	2/2/0/0	1/0/0/0
17	Y	Y/Y/Y/Y	Y/Y/Y/Y	N	Y/N/N/N	N/N/N/N	0	1/0/0/0	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
18	Y	Y/Y/Y/Y	Y/Y/Y/Y	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
19	Y	Y/Y/Y/Y	Y/Y/Y/Y	Y	Y/N/Y/Y	N/N/Y/Y	1	1/0/2/3	0/0/2/2	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0
20	Y	Y/Y/Y/Y	Y/Y/Y/Y	Y	N/Y/N/Y	N/N/N/N	1	0/3/0/3	0/0/0/0	N	N/N/N/N	N/N/N/N	0	0/0/0/0	0/0/0/0

^aReference
^bReader 1
^cReader 2
^dReader 3
^eReader 4
^fYes
^gNo
^hMultiple (> 5)

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