Table 3 Measured dose rates and calculated effective half-lives at different time points
From: External radiation exposure, excretion, and effective half-life in 177Lu-PSMA-targeted therapies
Time point | 2 ± 0.3 h | 3.9 ± 0.7 h | 24.2 ± 0.7 h | 45.7 ± 2.1 h | 67.7 ± 2.3 ha |
|---|---|---|---|---|---|
Dose rate [μSv/h] (measured at a distance of 2 m) | |||||
Mean | 3.6 | 2.8 | 1.6 | 1.1 | 0.7a |
Std. Dev. | 0.7 | 0.6 | 0.6 | 0.5 | 0.4a |
Min | 2.2 | 1.3 | 0.5 | 0.4 | 0.1a |
Max | 5.0 | 3.8 | 1.4 | 2.3 | 2.1a |
Calculated effective half-life T1/2eff | |||||
Mean | – | – | 26.0 | 40.5 | 38.4a |
Std. Dev. | – | – | 12.4 | 15.8 | 9.6a |
Min | – | – | 11.0 | 21.7 | 25.7a |
Max | – | – | 73.5 | 85.7 | 74.5a |