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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: Synthesis and preclinical evaluation of novel 18F-labeled Glu-urea-Glu-based PSMA inhibitors for prostate cancer imaging: a comparison with 18F-DCFPyl and 18F-PSMA-1007

Fig. 2

a PSMA affinities of the cold EuE-based inhibitors, F-DCFPyl and F-PSMA-1007. Internalization of the 18F-labeled EuE-based PSMA inhibitors, EuE-k-18F-FBOA and EuE-k-β-a-18F-FPyl in comparison to 18F-DCFPyl and 18F-PSMA-1007. b Lipophilicity and HSA-binding of EuE-k-18F-FBOA, EuE-k-β-a-18F-FPyl, 18F-DCFPyl, and 18F-PSMA-1007. *Specific internalization of the reference compound ((125I)I-BA)KuE assayed in a parallel experiment and used for data normalization

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