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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: Synthesis and preclinical evaluation of novel 18F-labeled Glu-urea-Glu-based PSMA inhibitors for prostate cancer imaging: a comparison with 18F-DCFPyl and 18F-PSMA-1007

Fig. 1

Synthesis and chemical structures of the 18F-labeled EuE-based inhibitors (EuE-k-18F-FBOA and EuE-k-β-a-18F-FPyl), 18F-DCFPyl and 18F-PSMA-1007 [1, 8, 15]. a Reaction conditions: 18F-FBA, EuE-k-AoA (3.3 μmol), 15 min at 60 °C [MeCN/water (1/1), (v/v), acidified with TFA to pH 2.5]. b Reaction conditions: 18F-FPyl-TFP, EuE-k-β-a/EuK/PSMA-1007 precursor (3.9 μmol), 15 min at 60 °C, NaHCO3 (5.5 mg) [MeCN/water; 2/1, (v/v)]

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