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Fig. 5 | EJNMMI Research

Fig. 5

From: Accuracy of tumor segmentation from multi-parametric prostate MRI and 18F-choline PET/CT for focal prostate cancer therapy applications

Fig. 5

Tumor segmentation results. Registered transaxial 18F-choline PET (a), ADC (b), T2W MRI (c), and 18F-choline fusion PET/MRI (d) are shown (SUV range 0–15). Contours of a Gleason 3+4 prostate cancer are displayed on corresponding slices obtained from registered histology (blue line and contour shadow) and compared to registrations from two human readers (red and green line and a contour obtained from 8F-choline PET (yellow)) using a semiautomatic thresholding method (e–h). A contour combining these three segmentations with an added safety margin of 5 mm (lime line) completely covers the histological tumor volume

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