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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: Noninvasive quantitation of rat cerebral blood flow using 99mTc-HMPAO—assessment of input function with dynamic chest planar imaging

Fig. 1

Input function of technetium-99m hexamethylpropyleneamine oxime (99mTc-HMPAO). a Typical chest planar radiographic image (left panel) and 99mTc-HMPAO images (middle and right panels) from the same rat. Region of interest (ROI) was manually surrounded on the 99mTc-HMPAO-planar image by a red circle using the corresponding radiographic image as a reference. b Typical time–activity curves of the radioactivity concentration in arterial blood samples (CBlood-sampling, dashed line) and in the heart on planar images (CBlood-planar, solid line). c Comparison of integrated radioactivity concentrations in arterial blood samples (AUCBlood-sampling) and that in the heart on planar images (AUCBlood-planar) until 19 s post-injection of 99mTc-HMPAO. Correlation between the AUC value determined by arterial blood sampling and that by chest dynamic planar imaging was assessed using Spearman’s rank correlation coefficient

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