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Table 3 I-124 codrituzumab radiation dose estimates

From: I-124 codrituzumab imaging and biodistribution in patients with hepatocellular carcinoma

  I-124 codrituzumab 10 mg (n = 14) I-124 codrituzumab 2.5–5 mg/kg (n = 7)
Target organ Mean cGy/37 MBq SD Mean cGy/37 MBq SD
 Adrenals 1.14 0.17 1.57 0.33
 Brain 0.60 0.14 0.84 0.19
 Breasts 0.71 0.12 1.01 0.21
 Gallbladder wall 1.18 0.18 1.60 0.33
 LLI wall 0.88 0.19 1.21 0.26
 Small intestine 0.90 0.19 1.25 0.27
 Stomach wall 0.92 0.17 1.29 0.28
 ULI wall 0.91 0.18 1.26 0.27
 Heart wall 3.82 0.55 5.60 1.20
 Kidneys 1.74 0.31 2.28 0.54
 Liver 2.43 0.38 3.19 0.64
 Lungs 1.87 0.34 2.44 0.48
 Muscle 0.75 0.15 1.05 0.22
 Ovaries 0.91 0.19 1.25 0.27
 Pancreas 1.13 0.18 1.56 0.33
 Red marrow 1.25 0.17 1.84 0.43
 Osteogenic cells 1.32 0.25 1.94 0.49
 Skin 0.55 0.12 0.77 0.17
 Spleen 2.14 0.42 2.76 0.63
 Testes 0.69 0.17 0.91 0.21
 Thymus 1.06 0.16 1.52 0.32
 Thyroid 4.16 2.19 3.66 1.88
 Urinary bladder wall 2.80 0.41 2.61 0.33
 Uterus 0.97 0.20 1.28 0.26
Total body 0.85 0.15 1.19 0.25
Effective dose equivalent (cGY/37 MBq) 1.65 0.21 2.13 0.36
Effective dose (cGy/37 MBq) 1.36 0.21 1.69 0.26