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Table 1 Patient demographics, pathology, and imaging

From: I-124 codrituzumab imaging and biodistribution in patients with hepatocellular carcinoma

Patient no.

Age/sex

Race

Child-Pugh score

Etiology

TNM

AJCC path grading

I-124 Czb baseline 10 mg

I-124 Czb second injection (mg/kg)

I-124 Czb third injection 10 mg

Day between IHC sample and I-124 Czb second injection

IHC H membrane

IHC H cytoplasmic

SUVmax tumor of biopsied lesion

1

63/M

White

A

None

IIIB

Poorly differentiated

Yes

5

ND

41

4

7

7

2

71/M

White

A

None

IV

Cannot be assessed

Yes

ND

ND

18

155

84

30.9

4

67/M

White

B

None

IV

Cannot be assessed

Yes

ND

ND

34

145

15

7.3

5

69/F

Asian

A

None

IIIC

Well differentiated

Yes

5

ND

46

30

25

5.8

6

64/M

White

A

None

IIIB

Cannot be assessed

Yes

ND

ND

11

0

15

NA

7

82/M

White

A

None

IIIB

Moderately differentiated

Yes

5

Yes

46

40

13

6.7

8

62/M

White

A

HepC

IV

Cannot be assessed

Yes

ND

ND

21

4

6

6.8

9

81/M

Asian

A

HepB

N/A

Well differentiated

Yes

2.5

Yes

38

5

85

8.1

10

58 M

Asian

A

HepB

I

Undifferentiated

Yes

ND

ND

10

165

150

12.8

11

68/F

A/A

A

HepC

IV

Cannot be assessed

Yes

ND

ND

14

1

25

4.9

13

58/M

A/A

A

HepC, Alcoholic

IIIA

Poorly differentiated

Yes

ND

ND

ND

ND

ND

ND

14

60/M

White

A

HepC

IV

Cannot be assessed

Yes

2.5

Yes

27

2

62

8.4

16

59/M

White

A

Alcoholic

IV

Moderately differentiated

Yes

2.5

ND

ND

ND

ND

ND

17

50/M

White

A

HepB

IV

Well differentiated

Yes

2.5

ND

ND

ND

ND

ND

  1. Abbreviations: path pathology, Czb codrituzumab, A/A African-American, TNM tumor, node, metastasis staging system, AJCC American Joint Committee on Cancer, IHC immunohistochemistry, ND not done