Skip to main content

Advertisement

Table 5 Stability of 68Ga conjugates at 37 °C in the presence of EDTA or DTPA at molar ratio 100:1 of competing ligand to conjugate (n = 3) after 120 min

From: Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging

Conjugate Linker % DOTA % of intact 68Ga conjugate ± SD
EDTA DTPA
31c (1) 1.6 92 ± 5 83 ± 1
33 (3) 1.6 90 ± 2 87 ± 1
34a (4) 0.6 77 ± 2 59 ± 1
34b (4) 1.2 80 ± 3 61 ± 1
35 (5) 3.5 78 ± 5 93 ± 1