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EJNMMI Research

Table 4 Stability of gallium-68 conjugates at 37 °C in the presence of different metal cations at 10− 2 M concentrations (n = 3)

From: Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging

Conjugate

Linker

% DOTA

% of intact 68Ga conjugate ± SD

Fe3+

Mg2+

Ca2+

31c

(1)

1.6

94 ± 3

92 ± 1

92 ± 5

33

(3)

1.6

94 ± 9

69 ± 2

99 ± 2

34a

(4)

0.6

88 ± 2

80 ± 3

70 ± 1

34b

(4)

1.2

84 ± 2

86 ± 2

90 ± 1

35

(5)

3.5

74 ± 2

85 ± 1

83 ± 8

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