Fig. 6From: Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195Illustration of radiotracer uptake, storage, and release mechanisms in PC12 cells. In PC12 cells, radiotracers (18F-LMI1195 or 131I-MIBG) that have been selectively taken up into the cells are first stored in storage vesicles and can be released by either high concentrations of KCl or reserpine. This procedure is Ca2+ dependentBack to article page