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Table 3 Mean relative sizes of activations in AR and eAR—both given as percent of the overall size of the auditory region. Moreover, a ratio of auditory to extra-auditory activations (AR/eAR) is given (bold). The three parameters are listed for different smoothing filter kernels (S) and thresholds for statistical inferences (p). About 1% activation in AR is reached with p < 0.001 for studies without anesthesia and p < 0.01 for those with anesthesia (italic type)

From: Feasibility of 15O-water PET studies of auditory system activation during general anesthesia in children

     S = [0 mm]3 S = [10 mm]3 S = [20 mm]3 S = [30 mm]3
Age group p < Anesthesia Stimulation AR (%) eAR (%) AR/eAR AR (%) eAR (%) AR/eAR AR (%) eAR (%) AR/eAR AR (%) eAR (%) AR/eAR
Adults 0.001 No PN 0.3 4.3 0.07 0.7 5.8 0.12 1.0 6.1 0.16 0.8 7.5 0.12
0.01 No PN 2.8 39.4 0.07 5.9 62.5 0.09 9.9 83.6 0.12 9.2 92.8 0.10
0.05 No PN 10.0 163.0 0.06 16.8 242.1 0.07 21.8 324.6 0.07 21.8 358.7 0.06
Children 0.001 Yes PN 0.2 2.4 0.05 0.2 2.5 0.02 0.0 4.3 0.03 0.4 5.0 0.02
0.01 Yes PN 1.1 22.0 0.04 1.2 23.0 0.03 1.3 25.4 0.02 1.6 31.0 0.05
0.05 Yes PN 4.5 108.6 0.04 4.9 112.0 0.04 5.0 114.1 0.03 4.9 120.2 0.03
Children 0.001 Yes CI 0.1 2.9 0.04 0.0 2.2 0.03 0.1 1.6 0.22 0.1 0.3 0.15
0.01 Yes CI 1.0 19.9 0.05 1.1 20.9 0.07 0.8 19.9 0.07 0.7 16.4 0.05
0.05 Yes CI 4.9 101.2 0.05 5.3 103.2 0.06 4.0 103.4 0.06 2.5 100.5 0.05
  1. AR auditory regions, eAR extra-auditory regions, PN promontory needle electrode, CI cochlear implant, S smoothing filter kernel