Feasibility of 15O-water PET studies of auditory system activation during general anesthesia in children

EJNMMI Research

Table 2 Comparison of peak height (t_max values) of auditory activations obtained with different scan durations (60 vs. 90s) and depending on anesthesia (no vs. yes). Mean values and standard deviations of t_max are given for different subgroups and smoothing kernels

Age group	Condition		T_max values and significance p, of difference
			S = [0 mm]³			S = [10 mm]³			S = [20 mm]³			S = [30 mm]³
	Anesthesia	Stimulation	60s.	90s	p	60s.	90s	p	60s.	90s	p	60s.	90s	p
Adults	No	PN	10.82 ± 2.39	12.06 ± 3.78	NS	11.68 ± 3.25	10.98 ± 5.24	NS	9.29 ± 3.91	8.54 ± 3.30	NS	7.14 ± 3.74	7.31 ± 6.57	NS
			NS	p = 0.0313		p = 0.0001	p = 0.0071		p = 0.0004	p = 0.0194		p = 0.0054	NS
Children	Yes	PN	9.56 ± 3.59	9.37 ± 3.43	NS	6.27 ± 2.52	6.86 ± 2.49	NS	4.81 ± 2.71	5.49 ± 4.27	NS	3.90 ± 2.54	4.09 ± 2.95	NS
Children	Yes	CI	10.06 ± 3.27	9.33 ± 2.99	NS	6.80 ± 2.10	8.07 ± 3.04	NS	5.28 ± 2.24	5.47 ± 2.96	NS	3.38 ± 1.16	4.40 ± 1.97	NS

PN promontory needle electrode, CI cochlear implant, S smoothing kernel, NS not significant