Positron emission tomography-magnetic resonance imaging (PET-MRI) for response assessment after radiation therapy of cervical carcinoma: a pilot study

EJNMMI Research

Table 2 Score for local residual tumor based on MRI (radiologist), PET (nuclear physician), and PET-MRI (consensus radiologist and nuclear physician) performed 3 months after treatment, quantitative measurements, reference standard, and outcome

Patient	MRI_post ADC_mean	PET_post SUV_max	MRI residual	PET residual	PET-MRI residual	Reference standard		Outcome
Patient	MRI_post ADC_mean	PET_post SUV_max	MRI residual	PET residual	PET-MRI residual	Local disease	Distant metastasis	Outcome
1	1.5	1.8	– –	–	– –	No	No	FU: NED 20 months
2	1.4	2.8	–	–	– –	No	No	FU: NED 26 months
3	1.3	2.9	–	+/−	– –	No	No	FU: NED 25 months
4	1.3	3.0	+	+	+/−	No	No	FU: NED 27 months
5	0.7	3.2	– –	+	–	Yes*	Yes	Palliation CHT
6	1.3	3.6	+	+ +	+ +	Yes	Yes	Palliation CHT, diseased
7	1.6	3.0	+	– –	+/−	No	Yes	Multiple meta, palliative
8	2.0	2.6	+/−	–	+	No	No	Salvage surgery, PA: no tumor. NED 21 months
9	1.5	5.1	+/−	+ +	+	Yes	No	Salvage surgery, FU: liver metastasis 3 months after surgery; palliative CHT
10	1.6	7.3	–	+	– –	No	Yes	Palliative CHT

Corresponding symbols: − −, definitely no residual tumor; −, probably no residual tumor; +/−, unclear possibly residual tumor; +, probably residual tumor; + +, definitely residual tumor/metastasis
Abbreviation: PA pathology, NED no evidence of disease, FU follow-up, CHT chemotherapy
*No pathology of local residual disease, growing mass on subsequent scans