Fig. 2

Dependence of the trapping rate on tracer equilibration and binding. a and d show voxel-scale trapping rate values versus voxel-scale TBR values for patients 1 and 2, respectively. b and e show the corresponding equilibration rates, calculated from Eq. (19); the solid lines indicate fits to Eq. (18), yielding k _eq=0.45 h ⁻¹ for pt. 1 and k _eq=0.52 h ⁻¹ for pt. 2. (c) and (f): The voxel-scale binding rates k _b calculated from Eq. (17) using the K _eq values shown in b and e