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Table 4 Effective doses for whole body in mSv and absorbed doses for normal organs in Gy after the administration of varying therapeutic activities of [64Cu]CuCl2 and 177Lu-PSMA

From: Biodistribution and radiation dosimetry of [64Cu]copper dichloride: first-in-human study in healthy volunteers

Estimations for [64Cu]CuCl2 (This work)
Activity (GBq) Whole body Liver Kidney Pancreas Lower large intestine Upper large intestine
4.0 226±24 1.46±0.35 0.32±0.11 0.38±0.07 0.64±0.19 0.55±0.16
8.0 452±48 2.93±0.70 0.64±0.21 0.76±0.13 1.27±0.38 1.10±0.31
12.0 678±72 4.39±1.04 0.96±0.32 1.14±0.20 1.91±0.56 1.66±0.47
Estimations for 177Lu-PSMA (Okamoto et al. 2017 [19])
Activity (GBq) Whole body Liver Kidney Parotic glands Submandibular glands Lacrimal glands
4.0 240±12 0.48±0.24 2.88±0.84 2.2±0.6 2.6±1.60 15.2±6.6
8.0 480±24 0.96±0.48 5.76±1.68 4.4±1.1 5.1±3.2 30.4±11.2
12.0 720±36 1.44±0.72 8.64±2.52 6.6±1.7 7.7±4.8 45.6±16.8