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Table 2 Mean organ absorbed radiation doses and effective doses normalized to the unit-injected activity (mean ± SD) of [64Cu]CuCl2 in healthy subjects

From: Biodistribution and radiation dosimetry of [64Cu]copper dichloride: first-in-human study in healthy volunteers

Organ Adult Male
Absorbed dose
(μGy/MBq)
Adult Female
Absorbed dose
(μGy/MBq)
Adrenals 30.0 ± 0.9 37.8 ± 0.7
Brain 4.2 ± 0.1 5.4 ± 0.5
Breasts 16.0 ± 1.3 20.3 ± 1.9
Gallbladder Wall 44.3 ± 2.9 54.1 ± 2.6
LLI Wall 153 ± 40 161 ± 26
Small Intestine 55.0 ± 11.0 62.6 ± 6.4
Stomach Wall 22.7 ± 1.3 29.1 ± 1.3
ULI Wall 131 ± 31 144 ± 23
Heart Wall 22.9 ± 0.6 29.8 ± 1.4
Kidneys 69.7 ± 15.7 90.0 ± 21.2
Liver 310 ± 67 421 ± 56
Lungs 20.8 ± 0.7 27.2 ± 1.4
Muscle 18.0 ± 1.6 22.5 ± 1.9
Ovaries* 24.3 ± 3.8 30.0 ± 0.8
Pancreas 83.4 ± 9.1 105 ± 14
Red Marrow 16.7 ± 1.3 19.9 ± 1.2
Osteogenic cells 32.9 ± 3.8 43.4 ± 5.0
Skin 14.6 ± 1.6 18.3 ± 1.9
Spleen 19.6 ± 1.5 25.3 ± 4.7
Testes 15.5 ± 2.2
Thymus 17.3 ± 1.6 22.0 ± 2.3
Thyroid 15.5 ± 2.0 18.8 ± 2.5
Urinary Bladder Wall 18.8 ± 2.6 21.4 ± 2.0
Uterus* 21.2 ± 3.0 26.3 ± 1.6
Total Body 26.9 ± 0.1 34.1 ± 0.2
Effective Dose (μSv/MBq) 51.2 ± 3.0 61.8 ± 5.2
  1. *Dosimetric calculations for men