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Fig. 6 | EJNMMI Research

Fig. 6

From: Pretargeting of internalizing trastuzumab and cetuximab with a 18F-tetrazine tracer in xenograft models

Fig. 6

Tumour uptake values for pretargeted cetuximab and trastuzumab (group A) and nonspecific uptake controls. Nonspecific uptake controls include pretargeted TCO-cetuximab with excess of non-radioactive TAF (blue), pretargeted TCO-cetuximab with excess of mAb (green), and TCO modified immunoglobulin G pretargeted with [18F]TAF (red). The results presented are at 4 h after [18F]TAF injection. The antibody was given 72 h prior to the injection of [18F]TAF. The values represent mean ± standard deviation. %ID/g = percentage injected dose/g. *p < 0.05 and **p < 0.005 (two-tailed paired t test done with IBM SPSS Statistics 22)

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