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Fig. 1 | EJNMMI Research

Fig. 1

From: Phantom validation of quantitative Y-90 PET/CT-based dosimetry in liver radioembolization

Fig. 1

Quantitative accuracy of 90Y–PET acquisitions. a Cylindrical phantom used for validating PET calibration uniformly filled with an activity concentration of 90YCl3 at a concentration of 273 ± 14 kBq mL−1 at the time of acquisition. Diethylenetriaminepentaacetic acid (DTPA) at a concentration of 100 μg g−1 was used to prevent binding of 90Y to the phantom PMMA walls. An overnight (16 h) single bed acquisition was performed. b Transversal slice of the NEMA IEC/2001 phantom used for the assessment of recovery coefficients needed for partial volume corrections. RCs are defined as the ratio of the measured activity concentration to true activity concentration. The phantom is provided with six fillable spheres of varying volume (0.52, 1.15, 2.57, 5.57, 11.49, and 26.52 mL), each filled with an activity concentration of 2.28 ± 0.11 MBq mL−1 at the time of acquisition. Sagittal (c) and coronal (d) view of the same phantom are also shown. e Recovery coefficients as a function of the volume of the sphere. RCs lie in the range 0.2–0.86 for the smallest sphere and largest sphere, respectively. The relative uncertainty was estimated to be 5% of the RC value, corresponding to the relative uncertainty associated with the activity as measured by the clinical radionuclide calibrator

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