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Table 3 PET/CT-derived distribution of 18F-TFB in healthy participants

From: Safety, pharmacokinetics, metabolism and radiation dosimetry of 18F-tetrafluoroborate (18F-TFB) in healthy human subjects

Organ 2 h post-injection (SUV) 3.5 h post-injection (SUV)
Males Females Males Females
Bone 0.80 ± 0.33 0.74 ± 0.20 1.4 ± 0.5* 1.3 ± 0.9*
Brain 0.39 ± 0.14 0.42 ± 0.15 0.74 ± 0.26* 0.61 ± 0.34*
Breast 2.8 ± 0.4 3.9 ± 1.4
Gallbladder 2.7 ± 1.5 3.7 ± 1.0 4.2 ± 1.7* 5.0 ± 1.6*
Intestines 2.9 ± 1.0 5.0 ± 2.7 4.4 ± 1.0 6.0 ± 3.1
Kidney 7.0 ± 2.5 5.6 ± 0.7 11 ± 3* 6.3 ± 2.4*
Liver 2.3 ± 1.0 2.7 ± 0.5 3.6 ± 1.2* 3.5 ± 1.6*
Lung 1.0 ± 0.4 1.2 ± 0.4 1.7 ± 0.6* 1.5 ± 0.8*
Muscle 0.71 ± 0.31 0.65 ± 0.35 0.96 ± 0.31* 0.78 ± 0.54*
Myocardium 3.2 ± 0.9 2.8 ± 0.5 5.0 ± 0.9* 3.8 ± 1.8*
Pancreas 3.4 ± 0.7 3.1 ± 1.7 6.2 ± 2.1 3.0 ± 1.2
Parotid 11 ± 9 20 ± 11 16 ± 13* 25 ± 15*
Spleen 4.1 ± 1.2 4.3 ± 1.0 6.3 ± 1.1* 5.5 ± 2.8*
Stomach 33 ± 15 72 ± 10 70 ± 32 51 ± 18
Thyroid 55 ± 31 50 ± 11 82 ± 42* 58 ± 12*
  1. Values are mean ± SD (n = 4)
  2. *p < 0.05 versus 2 h