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EJNMMI Research

Table 1 Pharmacokinetics of 18F-TFB in healthy participants

From: Safety, pharmacokinetics, metabolism and radiation dosimetry of 18F-tetrafluoroborate (18F-TFB) in healthy human subjects

Parametera

3-exponential fit parameter estimates

Males

Females

A 1 (SUV)

27.9 ± 9.5

23.2 ± 29.3

k 1 (min−1)

7.6 ± 2.8

9.7 ± 6.8

A 2 (SUV)

8.7 ± 3.0

6.8 ± 2.0

k 2 (min−1)

0.64 ± 0.36

0.44 ± 0.09

A 3 (SUV)

5.9 ± 1.6

5.1 ± 0.3

k 3 (min−1)

0.023 ± 0.023

0.016 ± 0.005

  1. Values are mean ± SD (n = 4)
  2. aSUV values derived from left-ventricular blood pool were fit to 3-exponential model: \( x={A}_1{e}^{-{k}_1t}+{A}_2{e}^{-{k}_2t}+{A}_3{e}^{-{k}_3t} \)
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