Fig. 5From: Oxygen-15 labeled CO2, O2, and CO PET in small animals: evaluation using a 3D-mode microPET scanner and impact of reconstruction algorithmsCBF (a), OEF (b), CMRO2 (c), and CBV (d) of each brain region according to each reconstruction method. The quantitative values obtained using each reconstruction were compared using a paired t test with Bonferroni’s correction (*P < 0.05, **P < 0.01). In the whole brain, OSEM3D-MAP revealed a 20% increase in CBF and a 15% increase in CMRO2, compared with the FBP findings, which resulted in a 5% decrease in the OEF. The differences in CBV among the three reconstruction methods were relatively smallBack to article page