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Table 3 Direct comparison of clinical Ra-223 and Tc-99m HMDP SPECT images

From: Ra-223 SPECT for semi-quantitative analysis in comparison with Tc-99m HMDP SPECT: phantom study and initial clinical experience

Patient no.

Age (year)

Weight (kg)

Injected activity (MBq)

Scan area

Bowel activity in scan area

Lesion site for LBR measurement

Order of collimator used for Ra-223 SPECT

Number of visible lesion sites

Tc

MEGP

HEGP

1

73

61

3.44

Chest

T12

MEGP, HEGP

5

1

3

2

68

64

3.35

Chest

+

T3, T8, L2, right 4th rib, left third rib

MEGP, HEGP

10

5

7

3

69

59

3.25

Chest

++

T3, T6, T10, L1, sternum

HEGP, MEGP

14

5

9

4

73

71

3.62

Pelvis

+++

L4, Iliac bone

HEGP, MEGP

5

2

4

5

67

61

3.17

Chest

+++

T3, T6, T8, T11, L2, L3, right 7th rib, left 6th rib, right clavicle

MEGP, HEGP

19

9

11

6

78

41

2.13

Abdomen

+++

T11, L2, L4, right 7th rib

MEGP, HEGP

9

4

5

7

69

67

3.68

Pelvis

+++

Sacrum

HEGP, MEGP

2

1

1

8

76

54

3.07

Abdomen

+++

T8, L2, L4

HEGP, MEGP

5

3

4

9

83

61

3.22

Abdomen

+++

T10, L4

MEGP, HEGP

7

2

2

10

74

68

3.70

Abdomen

++

T4, T9, L2, left 2nd rib

HEGP, MEGP

8

4

5

  1. Bowel activity was classified as (−) no uptake, (+) weaker than uptake in the metastatic sites, (++) comparable to uptake in the metastatic sites, (+++) stronger than uptake in the metastatic sites
  2. T thoracic spine, L lumbar spine, MEGP medium-energy general-purpose, HEGP high-energy general-purpose, LBR lesion-to-background ratio