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Table 3 Direct comparison of clinical Ra-223 and Tc-99m HMDP SPECT images

From: Ra-223 SPECT for semi-quantitative analysis in comparison with Tc-99m HMDP SPECT: phantom study and initial clinical experience

Patient no. Age (year) Weight (kg) Injected activity (MBq) Scan area Bowel activity in scan area Lesion site for LBR measurement Order of collimator used for Ra-223 SPECT Number of visible lesion sites
Tc MEGP HEGP
1 73 61 3.44 Chest T12 MEGP, HEGP 5 1 3
2 68 64 3.35 Chest + T3, T8, L2, right 4th rib, left third rib MEGP, HEGP 10 5 7
3 69 59 3.25 Chest ++ T3, T6, T10, L1, sternum HEGP, MEGP 14 5 9
4 73 71 3.62 Pelvis +++ L4, Iliac bone HEGP, MEGP 5 2 4
5 67 61 3.17 Chest +++ T3, T6, T8, T11, L2, L3, right 7th rib, left 6th rib, right clavicle MEGP, HEGP 19 9 11
6 78 41 2.13 Abdomen +++ T11, L2, L4, right 7th rib MEGP, HEGP 9 4 5
7 69 67 3.68 Pelvis +++ Sacrum HEGP, MEGP 2 1 1
8 76 54 3.07 Abdomen +++ T8, L2, L4 HEGP, MEGP 5 3 4
9 83 61 3.22 Abdomen +++ T10, L4 MEGP, HEGP 7 2 2
10 74 68 3.70 Abdomen ++ T4, T9, L2, left 2nd rib HEGP, MEGP 8 4 5
  1. Bowel activity was classified as (−) no uptake, (+) weaker than uptake in the metastatic sites, (++) comparable to uptake in the metastatic sites, (+++) stronger than uptake in the metastatic sites
  2. T thoracic spine, L lumbar spine, MEGP medium-energy general-purpose, HEGP high-energy general-purpose, LBR lesion-to-background ratio