Fig. 3

a–d Contrast-enhanced CT (a, b both axial) or post-contrast T1-weighted fat-saturated magnetic resonance imaging (MRI) (c coronal and d axial) representative images of the four chRCCs included in this study. e–h Corresponding ^99mTc-sestamibi SPECT/CT images of the same tumors demonstrating the highly variable degree of uptake seen in this tumor type. Tumors are denoted by yellow arrowheads. The tumors in (a/e) and (b/f) were qualitatively considered cold, whereas the tumors in (c/g) and (d/h) were qualitatively considered hot. Note the intense scatter activity from radiotracer in the common bile duct in (f) that must be visually excluded from the tumor to allow for accurate interpretation