Early assessment of response to induction therapy in acute myeloid leukemia using 18F-FLT PET/CT

EJNMMI Research

Table 5 Clinical outcome of 10 patients

Patient no.	Visual ¹⁸F-FLT uptake	FU BM result	Following treatment after induction	Relapse	Time to relapse (months)	Death	Follow-up time (months)
1	−	CR	Consolidation and PBSCT	No	16	Yes^a	16
2	−	CRi	Consolidation	Yes	7	Yes	18
3	−	CR	Consolidation	No	34	No	34
4	+	RD	Re-induction	–^b	–^b	Yes	3
5	−	CR	Consolidation	No	29	No	29
6	+	CR	Consolidation	Yes	–^c	Yes	17
7	+	CR	Consolidation	Yes	10	Yes	11
8	+	RD	Re-induction and consolidation	No	23	No	23
9	+	CR	Consolidation	No	21	No	21
10	−	CR	Consolidation	No	21	No	21

PBSCT peripheral stem cell transplantation
^aPatient 1 died from graft-versus-host disease
^bPatient 4 had never achieved a CR/CRi after initial induction therapy
^cPatient 6 had strongly suspected but unconfirmed relapse 10 months from the start of induction therapy