Table 2 Results from applying the correction described in Eq. (11) to DVR values obtained from Logan ref. and [18F]MNI-659. When the slope of the Bland-Altman plot ≠0, no average difference can be calculated due to proportionality bias
From: Revisiting the Logan plot to account for non-negligible blood volume in brain tissue
| Â | Linear regression | Bland-Altman | % Diffference | |||||
|---|---|---|---|---|---|---|---|---|
Slope | Intercept | r 2 | Slope | RC | Avg (SD) | t test (p) | ||
With pallidum | No correction | 0.74 | 0.81 | 0.93 | p < 1e − 8 | 1.3 | – | – |
Measured α | 0.91 | 1.00 | 0.93 | p = 0.10 | 1.1 | −24.7 (20.4) | < 1e − 11 | |
Calculated α | 0.89 | 0.71 | 0.95 | p < 0.01 | 0.9 | – | – | |
Without pallidum | No correction | 0.83 | 0.59 | 0.96 | p < 1e − 4 | 0.87 | – | – |
Measured α | 1.01 | 0.73 | 0.95 | p = 0.32 | 0.79 | −24.8 (20.4) | < 1e − 11 | |
Calculated α | 0.98 | 0.47 | 0.98 | p = 0.61 | 0.46 | −13.4 (15.5) | < 1e − 4 | |