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Table 1 Biodistribution of 4-[18F]FEBZA in mice bearing tumor xenografts

From: Selective targeting of melanoma using N-(2-diethylaminoethyl) 4-[18F]fluoroethoxy benzamide (4-[18F]FEBZA): a novel PET imaging probe

  %IA/g tissue (mean ± SD)
Organ B16F1 tumor HT-29 tumor C-32 tumor
  1 h 2 h 1 h 2 h 1 h 2 h
(n = 6) (n = 5) (n = 3) (n = 3) (n = 3) (n = 3)
Liver 3.25 ± 0.34 2.28 ± 0.49 4.84 ± 0.95 2.50 ± 0.29 3.11 ± 0.49 1.99 ± 0.12
Spleen 2.24 ± 0.36 1.58 ± 0.18 2.11 ± 0.25 1.51 ± 0.12 1.96 ± 0.38 1.22 ± 0.08
Lung 2.12 ± 0.17 1.49 ± 0.49 2.19 ± 0.33 1.63 ± 0.16 1.94 ± 0.67 1.33 ± 0.35
Heart 2.82 ± 0.25 2.12 ± 0.58 2.52 ± 0.12 2.19 ± 0.37 2.52 ± 0.15 1.75 ± 0.35
Kidneys 3.10 ± 0.28 2.20 ± 0.38 2.91 ± 0.24 2.08 ± 0.29 2.85 ± 0.37 1.84 ± 0.12
Bone 3.78 ± 0.45 5.45 ± 0.98 3.83 ± 0.39 5.71 ± 1.11 3.47 ± 0.78 5.09 ± 0.72
Sm. Intestine 2.49 ± 0.25 1.60 ± 0.31 1.98 ± 0.62 1.42 ± 0.10 2.23 ± 0.21 1.33 ± 0.06
Pancreas 2.48 ± 0.35 1.73 ± 0.14 2.41 ± 0.26 1.56 ± 0.18 2.49 ± 0.42 1.40 ± 0.10
Muscles 1.51 ± 0.21 1.14 ± 0.21 1.61 ± 0.28 1.40 ± 0.24 2.35 ± 1.06 1.05 ± 0.14
Brain 2.55 ± 0.61 2.25 ± 0.50 1.68 ± 0.18 1.52 ± 0.28 1.87 ± 0.21 1.36 ± 0.17
Adrenals 1.10 ± 0.36 0.88 ± 0.06 1.07 ± 0.08 0.91 ± 0.19 1.26 ± 0.39 0.77 ± 0.18
Blood 3.06 ± 0.52 2.51 ± 0.93 2.80 ± 0.26 2.29 ± 0.23 3.22 ± 0.64 2.40 ± 0.30
Tumor 8.66 ± 1.02 7.47 ± 1.34 3.68 ± 0.47 3.07 ± 0.36 3.91 ± 0.23 2.53 ± 0.19