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Table 2 Mean absorbed doses to normal organs and tumor for 225Ac-DOTA-anti-PD-L1-BC (15 kBq, 3 mg/kg)

From: Pharmacokinetics, microscale distribution, and dosimetry of alpha-emitter-labeled anti-PD-L1 antibodies in an immune competent transgenic breast cancer model

Organ Mean absorbed dose (mGy/kBq)
Blood 80.4
Heart 42.5
Lungs 53.0
Liver 738
Spleen 615
Kidneysa 138
Stomach 30.2
Intestine 42.8
Bone 69.7
Thymus 282
Muscle 11.8
BAT 57.5
Tumor 141
  1. aIncludes contribution from free 213Bi and 225Ac-DOTA-anti-PD-L1-BC