Skip to main content

Table 1 Intra- and inter-reader coefficients of variation using VOI/ROIs [median (range)]

From: Towards standardization of 18F-FET PET imaging: do we need a consistent method of background activity assessment?

  Simple ROI Spherical VOI Crescent VOI Friedman test
Intra-reader variabilities
 Overall group 3.69% (1.90–7.05%) 4.20% (1.74–8.30%) 1.52% (0.48–3.78%) p < 0.001
 Reader #1 4.03% (1.90–7.05%) 4.83% (2.58–8.30%) 1.04% (0.55–3.00%) p < 0.001
 Reader #2 5.16% (2.37–6.23%) 4.38% (2.79–5.98%) 1.49% (0.97–2.25%) p < 0.001
 Reader #3 2.86% (2.07–5.38%) 2.72% (1.74–3.53%) 1.19% (0.48–2.27%) p < 0.001
 Reader #4 2.99% (2.23–4.20%) 3.97% (2.59–6.68%) 2.06% (1.11–2.75%) p < 0.001
 Reader #5 2.62% (1.95–4.06%) 3.09% (2.02–5.04%) 1.05% (0.39–2.42%) p < 0.001
 Reader #6 4.74% (2.42–6.96%) 5.46% (3.04–6.57%) 1.97% (1.07–3.78%) p < 0.001
Inter-reader variabilities
 Overall group 3.83% (1.80–7.46%) 4.02% (1.47–6.32%) 2.14% (1.05–7.23%) p = 0.001