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EJNMMI Research

Table 1 Comparison of 11C-methionine uptake according to metabolic tumor volume

From: Optimization of diagnostic performance for differentiation of recurrence from radiation necrosis in patients with metastatic brain tumors using tumor volume-corrected 11C-methionine uptake

MTV (cm3)

T/N ratio (mean ± SD (range))

P value

Recurrence

Radiation necrosis

≤ 0.5 (n = 15)

1.31 ± 0.10 (1.20–1.47)

1.19 ± 0.09 (1.08–1.33)

0.037

> 0.5, ≤ 4.0 (n = 35)

1.93 ± 0.61 (1.35–4.00)

1.47 ± 0.18 (1.21–1.88)

0.001

> 4.0 (n = 27)

2.92 ± 1.28 (1.62–5.89)

1.65 ± 0.16 (1.48–1.84)

0.008

  1. T/N ratio tumor to normal tissue ratio, MTV metabolic tumor volume
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