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Table 1 Comparison of 11C-methionine uptake according to metabolic tumor volume

From: Optimization of diagnostic performance for differentiation of recurrence from radiation necrosis in patients with metastatic brain tumors using tumor volume-corrected 11C-methionine uptake

MTV (cm3) T/N ratio (mean ± SD (range)) P value
Recurrence Radiation necrosis
≤ 0.5 (n = 15) 1.31 ± 0.10 (1.20–1.47) 1.19 ± 0.09 (1.08–1.33) 0.037
> 0.5, ≤ 4.0 (n = 35) 1.93 ± 0.61 (1.35–4.00) 1.47 ± 0.18 (1.21–1.88) 0.001
> 4.0 (n = 27) 2.92 ± 1.28 (1.62–5.89) 1.65 ± 0.16 (1.48–1.84) 0.008
  1. T/N ratio tumor to normal tissue ratio, MTV metabolic tumor volume