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Table 1 Characteristics of study cohort at baseline (n = 32)

From: Clinical and imaging-based prognostic factors in radioembolisation of liver metastases from colorectal cancer: a retrospective exploratory analysis

Characteristic

n (%) unless indicated otherwise

Age in years, median (range)

63 (37–86)

Sex

 Male

23 (72%)

 Female

9 (28%)

BMI, median (range)

26 (20–38)

Primary site

 Colon

23 (72%)

 Rectum

9 (28%)

Definitive treatment to primary tumour

26 (81%)

Hepatic tumour burdena, median (range)

9 (1–46)

Hepatic tumour burdena > 25%

4 (13%)

Extrahepatic metastasesb

23 (72%)

Location of extrahepatic metastases

 

 Lungs alone

13

 Lung and lymph nodes

2

 Lymph nodes alone

5

 Other

3

Prior therapies

 Lines of chemotherapy

 1

9 (28%)

 2

22 (69%)

 Anti-VEGF/EGFR mAb

28 (88%)

 Hepatic resection

11 (34%)

 RFA/SBRTc to liver

2 (6%)

 Isolated liver oxaliplatin

1 (3%)

 Radiotherapy to extrahepatic sites

6 (19%)

RAS mutation statusd

 Wild type

14 (44%)

 Mutant

10 (31%)

 Unknown

8 (25%)

Treatment to both liver lobes

19 (59%)

Prescribed amount of 90Y for treatment in GBq, median (range)e

1.68 (0.42–2.08)

Time to follow-up FDG PET/CTe in days, median (range)

56 (38–80)

  1. aAs measured by the MeVis® radiological service (MeVis Medical Solutions AG, Bremen, Germany), based on contrast enhanced CT performed at the time of baseline FDG PET/CT
  2. bDetected on FDG PET/CT
  3. cRFA, Radiofrequency ablation; SBRT, stereotactic body radiation therapy
  4. dKRAS/NRAS where tested
  5. eFrom sub-cohort of 22 patients with analysable lesion data only