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Table 2 Residence times, organ absorbed doses and EDs according ICRP60 and ICRP103 for 30-min and 1-h urinary voiding cycles in men. Extrapolated organ dose in female and defence person is reported for 1-h urinary voiding cycle only

From: First in-human radiation dosimetry of 68Ga-NODAGA-RGDyK

   Patient cohort (n = 5 male) Female Reference
Residence time 0.5-h voiding 1-h voiding 1-h voiding
Target organ Mean
(hours)
SD Dose
(mGy/MBq)
SD Dose
(mGy/MBq)
SD Dose
(mGy/MBq)
Dose
(mGy/MBq)
Adrenals    6.40E−03 5.42E−04 6.42E−03 5.37E−04 8.18E−03 7.30E−03
Brain 3.20E−03 7.09E−04 1.77E−03 2.64E−04 1.77E−03 2.64E−04 2.15E−03 1.96E−03
Breasts    4.58E−03 2.99E−04 4.58E−03 2.96E−04 5.86E−03 5.22E−03
Gallbladder wall    7.01E−03 6.41E−04 7.07E−03 6.44E−04 8.69E−03 7.88E−03
LLI walla 8.87E−03 2.38E−03 2.05E−02 4.03E−03 2.12E−02 4.04E−03 2.41E−02 2.27E−02
Small intestinea 4.52E−02 1.14E−02 3.01E−02 6.43E−03 3.03E−02 6.45E−03 3.54E−02 3.29E−02
Stomach walla 6.16E−03 2.06E−03 1.13E−02 1.95E−03 1.13E−02 1.97E−03 1.36E−02 1.25E−02
ULI walla 1.16E−02 3.35E−03 1.85E−02 3.78E−03 1.87E−02 3.77E−03 2.18E−02 2.03E−02
Heart walla 1.41E−02 3.12E−03 1.29E−02 1.83E−03 1.29E−02 1.83E−03 1.53E−02 1.41E−02
Kidneys 2.86E−02 7.27E−03 4.63E−02 1.14E−02 4.64E−02 1.13E−02 5.06E−02 4.85E−02
Liver 5.11E−02 1.31E−02 1.55E−02 3.64E−03 1.56E−02 3.61E−03 2.08E−02 1.82E−02
Lungs 3.01E−02 3.92E−03 1.55E−02 1.90E−03 1.55E−02 1.90E−03 1.93E−02 1.74E−02
Muscle    5.28E−03 3.72E−04 5.45E−03 3.87E−04 6.88E−03 6.17E−03
Ovaries    N/A N/A N/A N/A 1.04E−02 9.28E−03
Pancreas 1.43E−03 7.16E−04 1.01E−02 3.70E−03 1.01E−02 3.68E−03 1.16E−02 1.09E−02
Red marrow 1.44E−02 2.81E−03 7.12E−03 3.84E−04 7.23E−03 3.79E−04 7.98E−03 7.61E−03
Osteogenic cells    8.57E−03 4.09E−04 8.64E−03 4.10E−04 1.17E−02 1.02E−02
Skin    4.36E−03 2.95E−04 4.43E−03 2.98E−04 5.60E−03 5.02E−03
Spleen 1.08E−02 7.26E−03 2.98E−02 1.85E−02 2.98E−02 1.85E−02 3.60E−02 3.28E−02
Testes    5.34E−03 3.77E−04 5.81E−03 4.43E−04 N/A 2.91E−03
Thymus    5.24E−03 3.33E−04 5.24E−03 3.33E−04 6.68E−03 5.96E−03
Thyroid 3.99E−04 2.10E−04 9.81E−03 4.29E−03 9.81E−03 4.29E−03 1.17E−02 1.08E−02
Urinary bladder walla 7.32E−02 1.51E−02 8.94E−02 1.73E−02 1.51E−01 2.99E−02 2.03E−01 1.77E−01
Uterus    N/A N/A N/A N/A 1.20E−02 1.09E−02
Total body 8.77E−01 6.75E−02 6.49E−03 5.24E−04 6.68E−03 5.32E−04 8.46E−03 7.57E−03
ED ICRP60    1.57E−02 1.50E−03 1.93E−02 1.95E−03 2.43E−02 2.07E−02
ED ICRP103    1.65E−02 1.68E−03 1.98E−02 1.98E−03 2.25E−02 1.90E−02
  1. aIrradiation from the organ content is accounted for residence time calculation