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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: Design, synthesis and evaluation in an LPS rodent model of neuroinflammation of a novel 18F-labelled PET tracer targeting P2X7

Fig. 2

Radiosynthetic route to [18F]EFB. a [18F]KF.K222, 15 min, 110 °C in DMSO followed by tC18 Sep-Pak SPE. b 2:1 w/w NaBH4/Co(OAc)2 in 2 mL:1 mL THF/H2O, 5 min followed by Strata-X-CW purification in acidic media. c Excess triethylamine, THF, 140 °C, HPLC purification and concentration on a light C18 Sep-Pak SPE cartridge

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