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Table 2 18F-florbetapir SUVRs in the healthy controls (HCs) and patients with major depressive disorder (MDD) with differing levels of treatment resistance in seven cortical VOIs and the global cortex

From: Beta-amyloid deposition in patients with major depressive disorder with differing levels of treatment resistance: a pilot study

Region HCs MDD patients P value
Mild treatment resistance Moderate-to-severe treatment resistance
Frontal     0.365
 Mean ± SD 1.09 ± 0.09 1.12 ± 0.11 1.11 ± 0.15  
 Median (IQR) 1.07 (1.04–1.16) 1.09 (1.06–1.15) 1.07 (1.03–1.15)  
Anterior cingulate     0.606
 Mean ± SD 1.21 ± 0.11 1.24 ± 0.12 1.21 ± 0.15  
 Median (IQR) 1.18 (1.13–1.30) 1.24 (1.16–1.33) 1.22 (1.11–1.29)  
Posterior cingulate     0.251
 Mean ± SD 1.31 ± 0.12 1.31 ± 0.16 1.36 ± 0.16  
 Median (IQR) 1.28 (1.21–1.43) 1.29 (1.24–1.41) 1.35 (1.27–1.44)  
Occipital     0.284
 Mean ± SD 1.15 ± 0.08 1.18 ± 0.08 1.21 ± 0.13  
 Median (IQR) 1.16 (1.09–1.21) 1.17 (1.14–1.23) 1.19 (1.12–1.24)  
Parietal     0.032*
 Mean ± SD 1.01 ± 0.08 1.08 ± 0.11 1.11 ± 0.15a*  
 Median (IQR) 1.03 (0.94–1.06) 1.06 (1.00–1.17) 1.08 (1.02–1.14)  
Precuneous     0.201
 Mean ± SD 1.02 ± 0.08 1.06 ± 0.1 1.10 ± 0.17  
 Median (IQR) 1.02 (0.95–1.09) 1.04 (1.00–1.10) 1.06 (0.99–1.13)  
Temporal     0.693
 Mean ± SD 1.03 ± 0.06 1.02 ± 0.07 1.03 ± 0.12  
 Median (IQR) 1.02 (1.00–1.07) 1.01 (0.99–1.04) 1.00 (0.95–1.08)  
Global     0.52
 Mean ± SD 1.13 ± 0.07 1.15 ± 0.09 1.16 ± 0.13  
 Median (IQR) 1.11 (1.07–1.16) 1.13 (1.11–1.19) 1.14 (1.09–1.18)  
  1. aSignificant difference as compared with HCs: *P < 0.05