Fig. 3

Representative 1TCM and 2TCM model fits. a Representative (n = 1) TAC and 1TCM and 2TCM model fits for the whole brain of an animal from the PS group. b Representative (n = 1) TACs and 1TCM and 2TCM model fits for the frontal cortex (square) and the pons (circle) of an animal from the TD group. The individual data points (black dots) and two models fits are displayed: the 1TCM (gray solid line) and the 2TCM (black solid line) with the separate compartments (free + non-displaceable, black dashed line; specific, black dotted line)