Skip to main content

Table 2 Mean absorbed dose calculations of 177Lu-octreotate in GOT1-bearing nude mice

From: Priming increases the anti-tumor effect and therapeutic window of 177Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1

Tissue

Mean absorbed dose per administered activity (Gy/MBq)

With priming, (5+) 10 MBq

Without priming, 15 MBq

Adrenals

0.11

0.079

Blood

0.00067

0.00069

Kidneys

0.25

0.32

Liver

0.014

0.011

Lungs

0.069

0.038

Pancreas

0.042

0.024

Spleen

0.023

0.012

Tumor

0.51

0.27a

  1. The mean absorbed dose per administered activity after 10 or 15 MBq 177Lu-octreotate (Gy/MBq) (with and without priming, n = 9/group), respectively. Values for the 5 + 10 MBq group were estimated from the values for the 10 MBq administrations only
  2. a n = 8