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EJNMMI Research
Fig. 6 | EJNMMI Research

Fig. 6

From: Priming increases the anti-tumor effect and therapeutic window of 177Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1

Fig. 6

Expression of genes associated with cell cycle regulation. Differential expression of genes associated with cell cycle regulation (a pro-proliferative genes, b anti-proliferative genes, c general cell cycle regulation-related genes) in tumor samples from animals treated with 15 or 5 + 10 MBq 177Lu-octreotate, compared with untreated controls after 24 h, 72 h, 168 h, and 41 days after the last injection. Transcripts with changed expression ≥1.5-fold and an adjusted p < 0.01 were considered significantly regulated; association to biological process was performed using the GO database with a p value cutoff of <0.05

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