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Fig. 4 | EJNMMI Research

Fig. 4

From: Priming increases the anti-tumor effect and therapeutic window of 177Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1

Fig. 4

MRI of GOT1 xenograft in the biodistribution and dosimetry study. a Relative mean tumor volume for 5 + 10 and 15 MBq groups vs. time after treatment. The mean tumor volume in the 5 + 10 MBq group decreased by 5.7%/day after treatment, whereas the corresponding value was 5.1%/day in the 15 MBq group. b The mean skewness of the tumor voxel histograms is shown vs. time after administration. The general trend was a shift towards more positive skewness before treatment, with a reversed direction after treatment, where the negative shift is more pronounced in the 15 MBq group (red line). The gray arrow indicates the injection of 5 and 15 MBq and the black arrow indicates injection of 10 MBq. Error bars indicate SD

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