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EJNMMI Research

Table 1 Estimated compartment model parameters

From: Dynamic PET evaluation of elevated FLT level after sorafenib treatment in mice bearing human renal cell carcinoma xenograft

 

K1 (mL/min/g)

k2 (1/min)

k3 (1/min)

k4 (1/min)

Vd (mL/g)

Control

0.547 ± 0.106

1.012 ± 0.284

0.082 ± 0.009

0.037 ± 0.006

0.556 ± 0.073

Sorafenib

0.231 ± 0.050

0.359 ± 0.060

0.111 ± 0.027

0.017 ± 0.003

0.641 ± 0.052

p value

<0.01

<0.01

<0.05

<0.01

N.S.

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