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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: Dynamic PET evaluation of elevated FLT level after sorafenib treatment in mice bearing human renal cell carcinoma xenograft

Fig. 2

Compartment model of [18F]FLT in the tumor tissue. K1, k2, k3, and k4 are the kinetic rate constants between the compartments. Cp blood concentration of [18F]FLT, Ce exchangeable [18F]FLT concentration in the tissue, Cm phosphorylated [18F]FLT metabolites in the tissue, Cmet concentration of [18F]FLT metabolites in the arterial plasma. FLTMP FLT-monophosphate, TLTDP FLT-diphosphate, FLTTP FLT-triphosphate, FLT-gluc FLT-glucuronide

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